Current appointment

2024–present

Postdoctoral Fellow, Rudebeck Lab

Icahn School of Medicine at Mount Sinai

Advisor: Peter Rudebeck, D.Phil. Research: circuit mechanisms of reinforcement learning in macaques.

Education

2019–2024

PhD in Neuroscience

Icahn School of Medicine at Mount Sinai

Advisor: Peter Rudebeck, D.Phil. Thesis: A comparative analysis of amygdala anatomy and physiology in mice, macaques, and man.

2015–2019

BS in Neuroscience and BA in Latin, summa cum laude

Mercer University

Research

2019–2024

Comparative anatomy of amygdala–frontal circuits

Used single-neuron projection mapping to characterize amygdala–frontal connectivity in macaques and mice, revealing species differences in branching projection patterns.

2019–2024

Hierarchy of intrinsic timescales across species

Analyzed neural activity across mice, macaques, and humans to study how intrinsic timescales vary across frontal and limbic regions.

2024–present

Circuit mechanisms of reinforcement learning in macaques

I study how amygdala–frontal circuits support credit assignment during reinforcement learning in macaques, combining behavioral tasks, electrophysiology, computational modeling, and pathway-specific manipulation.

Publications

2026

London L, Love M, Zeisler ZR, et al. Dataset of cortical and subcortical single neuron activity during value-based tasks in macaque monkey. Scientific Data 13, 989 (2026).

DOI

2025

Zeisler ZR, Love M, Rutishauser U, Stoll FM, Rudebeck PH. Consistent hierarchies of single-neuron timescales in mice, macaques, and humans. Journal of Neuroscience 45(19), e2155242025 (2025).

DOIPubMed

2025

Zeisler ZR, Rudebeck PH. Evolutionary road to primate prefrontal cortex. In: The Evolution of Nervous Systems, 3rd ed., Vol. 3, 338–362. Elsevier (2025).

DOI

2024

Zeisler ZR, Heslin KA, Stoll FM, et al. Comparative basolateral amygdala connectomics reveals dissociable single-neuron projection patterns to frontal cortex in macaques and mice. Current Biology 34, 3249–3257 (2024).

DOIPubMed

2023

Zeisler ZR, London L, Janssen WG, Fredericks JM, Elorette C, Fujimoto A, Zhan H, Russ BE, Clem RL, Hof PR, Stoll FM, Rudebeck PH. Single basolateral amygdala neurons in macaques exhibit distinct connectional motifs with frontal cortex. Neuron 111(20), 3307–3320.e5 (2023).

DOIPubMed

Recognition

2025

Cajal Club Krieg Cortical Scholar Award

Awarded in 2025 for contributions to research on cortical structure and function.

Zach Zeisler receiving the Cajal Club Krieg Cortical Scholar Award in 2025
Receiving the Cajal Club Krieg Cortical Scholar Award, 2025.

About the Krieg Cortical Kudos

Presentations

November 2025

Society for Neuroscience Nanosymposium

Neural circuit mechanisms of bottom-up reward learning. — San Diego, CA

September 2025

New York Memory Hub Conference

The neural circuits and mechanisms of short-term memory during reward learning. — New York, NY

March 2025

Janelia Mechanistic Cognitive Neuroscience Workshop

Circuit mechanisms of bottom-up influences on reversal learning in macaques. — Ashburn, VA

March 2025

COSYNE

Neural circuit mechanisms of bottom-up reward learning. — Montreal, QC

September 2024

From Neuroscience to Artificially Intelligent Systems

Neural dynamics supporting affective reward learning. — Cold Spring Harbor, NY

Teaching, mentoring, and outreach

2020–2023

Project SHORT — Director of Outreach

Mount Sinai

Led outreach, website redesign, and student mentorship for Project SHORT, a volunteer program supporting students applying to graduate or medical school.

2019–2023

MiNDS — Mentoring in Neuroscience Discovery at Sinai

Mount Sinai

Participated in Brain Awareness Week programming, neuroscience education, and STEM outreach in New York City.

2021 · 2022

Teaching Assistant, Behavioral and Cognitive Neuroscience

Mount Sinai · Spring 2021 and Spring 2022

Teaching assistant for a graduate course in behavioral and cognitive neuroscience; developed course materials and mentored graduate students.